Microencapsulation of fish oil using supercritical antisolvent process
نویسندگان
چکیده
منابع مشابه
Polymer Encapsulation of Fine Particles by a Supercritical Antisolvent Process
Coating and encapsulation of fine particles with polymer using a supercritical antisolvent (SAS) coating process was investigated in this research. Synthesized submicron silica particles were used as host particles and poly(lactide-co-glycolide) (PLGA), a biodegradable polymer used for controlled release of drugs, was chosen as the coating material. In the SAS coating process a suspension of si...
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BACKGROUND The aim of this study was to improve the physicochemical properties and bioavailability of poorly water-soluble sirolimus via preparation of a solid dispersion of nanoparticles using a supercritical antisolvent (SAS) process. METHODS First, excipients for enhancing the stability and solubility of sirolimus were screened. Second, using the SAS process, solid dispersions of sirolimus...
متن کاملFabrication and evaluation of valsartan–polymer– surfactant composite nanoparticles by using the supercritical antisolvent process
The aim of this study was to fabricate valsartan composite nanoparticles by using the supercritical antisolvent (SAS) process, and to evaluate the correlation between in vitro dissolution and in vivo pharmacokinetic parameters for the poorly water-soluble drug valsartan. Spherical composite nanoparticles with a mean size smaller than 400 nm, which contained valsartan, were successfully fabricat...
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The aim of this study was to develop celecoxib-polyvinylpyrrolidone (PVP) solid dispersion nanoparticles with and without surfactant using the supercritical antisolvent (SAS) process. The effect of different surfactants such as gelucire 44/14, poloxamer 188, poloxamer 407, Ryoto sugar ester L1695, and d-α-tocopheryl polyethylene glycol 1000 succinate (TPGS) on nanoparticle formation and dissolu...
متن کاملSupercritical antisolvent precipitation of PHBV microparticles.
The micronization of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) from organic solutions using supercritical antisolvent (SAS) technique has been successfully achieved. SAS experiments were carried out at different operational conditions and microspheres with mean diameters ranging from 3 to 9 microm were obtained. The effect of CO(2) and liquid flow, temperature and pressure on particle...
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ژورنال
عنوان ژورنال: Journal of Food and Drug Analysis
سال: 2017
ISSN: 1021-9498
DOI: 10.1016/j.jfda.2016.11.017